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Antibody Identity card

AID (Activation-induced cytidine deaminase) Protein

Protein information

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. AICDA is specifically expressed and active in germinal center-like B cells. AID, the protein product of AICDA, is required for several crucial steps in B‐cell terminal differentiation, which is necessary for efficient antibody responses. AICDA may also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.

Protein link information

Validation / characterisation

  • Working
  • No conclusive
  • Not working
  • Not tested