mAbs Against HUMAN Protein
|CONTACT INFORMATION:||University of Oxford marketed by Ximbio.com|
|TYPE:||mouse anti human|
|CLONE NAME:||CD11C 118/A5|
|PROTEIN:||Integrin subunit alpha X|
|ANTIGEN USED:||Synthetic peptide conjugated to KLH corresponding to the C terminus of human CD11C: ANGQIAPENGTQTPSP|
|PREPARATION AND STORAGE:||Aliquot and store at 4C. Do not freeze|
The integrin alpha X chain protein (CD11c) belongs to the ß2 integrin subfamily. Integrins are cell surface receptors composed of a heterodimer containing an a and ß subunit. CD11c (the a subunit) combines with CD18 (the ß subunit) to form the leukocyte specific integrin inactivated-C3b receptor 41,2. CD11c is known to be expressed on monocytes/macrophages, granulocytes, activated B cells, in spleen and in bone marrow.