mAbs Against HUMAN Protein
CD11C
| STATUS: | |
|---|---|
| CONTACT INFORMATION: | University of Oxford marketed by Ximbio.com |
| TYPE: | mouse anti human |
| CLONE NAME: | CD11C 118/A5 |
| PROTEIN: | Integrin subunit alpha X |
| PROTEIN WEB: | https://www.omim.org/entry/151510 |
| ANTIGEN USED: | Synthetic peptide conjugated to KLH corresponding to the C terminus of human CD11C: ANGQIAPENGTQTPSP |
| FUSION PARTNER: | NS0 |
| ISOTYPE: | IgG2b |
| SPECIES REACTIVITY: | Human |
| PREPARATION AND STORAGE: | Aliquot and store at 4C. Do not freeze |
| COMMERCIALIZED BY: | Ximbio.com |
| APP RECOMMENDED: | IHC |
Description
The integrin alpha X chain protein (CD11c) belongs to the ß2 integrin subfamily. Integrins are cell surface receptors composed of a heterodimer containing an a and ß subunit. CD11c (the a subunit) combines with CD18 (the ß subunit) to form the leukocyte specific integrin inactivated-C3b receptor 41,2. CD11c is known to be expressed on monocytes/macrophages, granulocytes, activated B cells, in spleen and in bone marrow.