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mAbs Against HUMAN Protein

FCGR2

STATUS:
CONTACT INFORMATION:University of Oxford marketed by Ximbio.com
TYPE:mouse anti human
CLONE NAME:2ZC115
PROTEIN:Fc gamma Recptor II (FCGR2, CD32)
PROTEIN WEB:https://www.omim.org/entry/604590
ANTIGEN USED:Hairy cell leukaemia cells
FUSION PARTNER:P3/NS1/1-Ag4.1
ISOTYPE:IgG2a
SPECIES REACTIVITY:Human
PREPARATION AND STORAGE:Aliquot and store at 4C. Do not freeze
COMMERCIALIZED BY:Ximbio.com
APP RECOMMENDED:IHC

Description

Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils.

Applications

IHC Techniques
IHC Techniques Clone Dilution Antibody concentration Antigen retrieval method Visualization kit +/- control Protein localization Positivity in other species Protocol
Frozen tissue and cytospins
Paraffin tissue
2ZC115 neat supernatant Tris EDTA Dako Envision Tonsil /
Immunofluorescence
Enlarge image
2ZC115 Tonsil
Tonsil stained with neat supernatant from 2ZC115 hybridoma, detection using Dako Envision kit, 4x power image
Enlarge image
2ZC115 Tonsil
Tonsil stained with neat supernatant from 2ZC115 hybridoma, detection using Dako Envision kit, 10x power image