mAbs Against HUMAN Protein
GlycophorinA
STATUS: | |
---|---|
CONTACT INFORMATION: | University of Oxford marketed by Ximbio.com |
TYPE: | mouse anti human |
CLONE NAME: | JC159A |
PROTEIN: | Glycophorin A |
PROTEIN WEB: | https://www.omim.org/entry/617922 |
ANTIGEN USED: | Membrane preparation from splenic hairy cell leukaemia cells |
FUSION PARTNER: | P3/NS1/1-Ag4.1 |
ISOTYPE: | IgG1 |
SPECIES REACTIVITY: | Human |
PREPARATION AND STORAGE: | Aliquot and store at 4C. Do not freeze |
COMMERCIALIZED BY: | Ximbio.com |
APP RECOMMENDED: | FACS IHC |
Description
Glycophorin A (GpA) is a 131 amino acid sialoglycoprotein that spans the membrane once and presents its amino-terminal end at the extra-cellular surface of the human red blood cell and precursor cells. It has been shown that glycophorins act as the receptor for Sandei virus and parvovirus.
References
J Clin Pathol. 1999 Dec;52(12):919-21.
Immunohistochemical identification of erythroid precursors in paraffin embedded bone marrow sections: spectrin is a superior marker to glycophorin.
Sadahira Y1, Kanzaki A, Wada H, Yawata Y.
PMID: 10711257
https://www.ncbi.nlm.nih.gov/pubmed/10711257