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Antibody Identity card

CD85a (LILRB3/ILT5) Protein

Protein information

CD85 is a group of Ig superfamily tansmembrane glycoproteins called Ig-Like Transcripts (ILTs) or Leukocyte Immunoglobulin-like Receptors (LIRs). CD85a is the 110kD member, known as ILT5, LILRB3. CD85a is found on the surface of monocytes/macrophages, granulocytes, NK cells and T-cell subset. CD85a binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.

Protein link information

Validation / characterisation

  • Working
  • No conclusive
  • Not working
  • Not tested