EuroMAbNet: European Monoclonal Antibodies NetworkEuroMAbNet. European Monoclonal Antibodies Network

☰ Menu

mAbs Against HUMAN Protein

CALLA

CONTACT INFORMATION:University of Oxford marketed by Ximbio.com
TYPE:mouse anti human
CLONE NAME:SS2/36
PROTEIN:Common Acute Lymphocytic Leukaemia Antigen (CALLA, CD10)
PROTEIN WEB:https://www.omim.org/entry/120520
ANTIGEN USED:Common acute lymphoblastic leukaemia cells
FUSION PARTNER:P3/NS1/1-Ag4.1
ISOTYPE:IgG1
SPECIES REACTIVITY:Human
PREPARATION AND STORAGE:Aliquot and store at 4C. Do not freeze
COMMERCIALIZED BY:Ximbio.com
APP RECOMMENDED:FACS IHC WB

DESCRIPTION

CALLA is expressed on B- and T- cell precursors, bone marrow stromal cells, lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). CALLA is a cell surface enzyme that inactivates a variety of peptides. SS2/36 is a marker for Acute Lymphocytic Luekaemia (ALL). CALLA is widely used for identification of "common" type Acute Lymphocytic Leukaemia (ALL).

REFERENCES

Majdic O, Sugita K, Stockinger H, Skrobal A, Knapp W (1987) Comparative evaluation of CD10 antibodies. In McMichael AJ, et al (eds) Leucocyte Typing III, Oxford University Press, Oxford, New York and Tokyo, p 488-9.