mAbs Against HUMAN Protein
CALLA
| STATUS: | |
|---|---|
| CONTACT INFORMATION: | University of Oxford marketed by Ximbio.com |
| TYPE: | mouse anti human |
| CLONE NAME: | SS2/36 |
| PROTEIN: | Common Acute Lymphocytic Leukaemia Antigen (CALLA, CD10) |
| PROTEIN WEB: | https://www.omim.org/entry/120520 |
| ANTIGEN USED: | Common acute lymphoblastic leukaemia cells |
| FUSION PARTNER: | P3/NS1/1-Ag4.1 |
| ISOTYPE: | IgG1 |
| SPECIES REACTIVITY: | Human |
| PREPARATION AND STORAGE: | Aliquot and store at 4C. Do not freeze |
| COMMERCIALIZED BY: | Ximbio.com |
| APP RECOMMENDED: | FACS IHC WB |
Description
CALLA is expressed on B- and T- cell precursors, bone marrow stromal cells, lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). CALLA is a cell surface enzyme that inactivates a variety of peptides. SS2/36 is a marker for Acute Lymphocytic Luekaemia (ALL). CALLA is widely used for identification of "common" type Acute Lymphocytic Leukaemia (ALL).
References
Majdic O, Sugita K, Stockinger H, Skrobal A, Knapp W (1987) Comparative evaluation of CD10 antibodies. In McMichael AJ, et al (eds) Leucocyte Typing III, Oxford University Press, Oxford, New York and Tokyo, p 488-9.