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mAbs Against HUMAN Protein

CD20

CONTACT INFORMATION:University of Oxford marketed by Ximbio.com
TYPE:mouse anti human
CLONE NAME:PDR78
PROTEIN:CD20
PROTEIN WEB:https://www.omim.org/entry/112210
ANTIGEN USED:Pokeweed mitogen-activated Burkitt's lymphoma cell lines.
FUSION PARTNER:P3/NS1/1-Ag4.1
ISOTYPE:IgG
SPECIES REACTIVITY:Human
PREPARATION AND STORAGE:Aliquot and store at 4C. Do not freeze
COMMERCIALIZED BY:Ximbio.com
APP RECOMMENDED:FACS IHC

DESCRIPTION

CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues.

REFERENCES

Ono N et al. 1997. CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI. Garland Publishing Inc., New York and London, p 135-137.