mAbs Against HUMAN Protein
|CONTACT INFORMATION:||University of Oxford marketed by Ximbio.com|
|TYPE:||mouse anti human|
|PROTEIN:||Fc gamma Recptor II (FCGR2, CD32)|
|ANTIGEN USED:||Hairy cell leukaemia cells|
|PREPARATION AND STORAGE:||Aliquot and store at 4C. Do not freeze|
|APP RECOMMENDED:||FACS IHC IP|
Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils.
PUBLICATION DESCRIBING ANTIBODY CHARACTERIZATION/VALIDATION
Immunology. 1986 Jan;57(1):71-6.
A new monoclonal antibody (KB61) recognizing a novel antigen which is selectively expressed on a subpopulation of human B lymphocytes.
Pulford K, Ralfkiaer E, MacDonald SM, Erber WN, Falini B, Gatter KC, Mason DY.