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mAbs Against HUMAN Protein

FCGR2

CONTACT INFORMATION:University of Oxford marketed by Ximbio.com
TYPE:mouse anti human
CLONE NAME:KB61
PROTEIN:Fc gamma Recptor II (FCGR2, CD32)
ANTIGEN USED:Hairy cell leukaemia cells
FUSION PARTNER:P3/NS1/1-Ag4.1
ISOTYPE:IgG1 kappa
SPECIES REACTIVITY:Human
PREPARATION AND STORAGE:Aliquot and store at 4C. Do not freeze
COMMERCIALIZED BY:Ximbio.com
APP RECOMMENDED:FACS IHC IP

DESCRIPTION

Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils.

PUBLICATION DESCRIBING ANTIBODY CHARACTERIZATION/VALIDATION

Immunology. 1986 Jan;57(1):71-6.
A new monoclonal antibody (KB61) recognizing a novel antigen which is selectively expressed on a subpopulation of human B lymphocytes.
Pulford K, Ralfkiaer E, MacDonald SM, Erber WN, Falini B, Gatter KC, Mason DY.
PMID: 3484721
https://www.ncbi.nlm.nih.gov/pubmed/3484721