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mAbs Against HUMAN Protein

HRX

CONTACT INFORMATION:University of Oxford marketed by Ximbio.com
TYPE:mouse anti human
CLONE NAME:HRX107
PROTEIN:Histone-lysine N-methyltransferase (HRX, MLL, ALL1, Htrx)
PROTEIN WEB:https://www.omim.org/entry/159555
ANTIGEN USED:Synthetic peptides corresponding to 839-854 of the HRX protein
FUSION PARTNER:P3/NS1/1-Ag4.1
ISOTYPE:IgM
SPECIES REACTIVITY:Human
PREPARATION AND STORAGE:Aliquot and store at 4C. Do not freeze
COMMERCIALIZED BY:Ximbio.com
APP RECOMMENDED:ChIP IHC IF WB

DESCRIPTION

The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Leukaemia through translocations that that result in its fusion with a variety of heterologous partners

PUBLICATION DESCRIBING ANTIBODY CHARACTERIZATION/VALIDATION

Blood. 1997 May 1;89(9):3361-70.
The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures.
Butler LH1, Slany R, Cui X, Cleary ML, Mason DY.
PMID: 9129043
https://www.ncbi.nlm.nih.gov/pubmed/9129043