mAbs Against HUMAN Protein
|CONTACT INFORMATION:||University of Oxford marketed by Ximbio.com|
|TYPE:||mouse anti human|
|PROTEIN:||Histone-lysine N-methyltransferase (HRX, MLL, ALL1, Htrx)|
|ANTIGEN USED:||Synthetic peptides corresponding to 839-854 of the HRX protein|
|PREPARATION AND STORAGE:||Aliquot and store at 4C. Do not freeze|
|APP RECOMMENDED:||ChIP IHC IF WB|
The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Leukaemia through translocations that that result in its fusion with a variety of heterologous partners
Publication describing antibody characterization/validation
Blood. 1997 May 1;89(9):3361-70.
The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures.
Butler LH1, Slany R, Cui X, Cleary ML, Mason DY.