mAbs Against HUMAN Protein
HRX
| STATUS: | |
|---|---|
| CONTACT INFORMATION: | University of Oxford marketed by Ximbio.com |
| TYPE: | mouse anti human |
| CLONE NAME: | HRX107 |
| PROTEIN: | Histone-lysine N-methyltransferase (HRX, MLL, ALL1, Htrx) |
| PROTEIN WEB: | https://www.omim.org/entry/159555 |
| ANTIGEN USED: | Synthetic peptides corresponding to 839-854 of the HRX protein |
| FUSION PARTNER: | P3/NS1/1-Ag4.1 |
| ISOTYPE: | IgM |
| SPECIES REACTIVITY: | Human |
| PREPARATION AND STORAGE: | Aliquot and store at 4C. Do not freeze |
| COMMERCIALIZED BY: | Ximbio.com |
| APP RECOMMENDED: | ChIP IHC IF WB |
Description
The HRX gene (also called MLL, ALL-1 or Htrx) located to chromosome band 11q23 is associated with specific subsets of acute Leukaemia through translocations that that result in its fusion with a variety of heterologous partners
Publication describing antibody characterization/validation
Blood. 1997 May 1;89(9):3361-70.
The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures.
Butler LH1, Slany R, Cui X, Cleary ML, Mason DY.
PMID: 9129043
https://www.ncbi.nlm.nih.gov/pubmed/9129043