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mAbs Against HUMAN Protein

Leu2

CONTACT INFORMATION:University of Oxford marketed by Ximbio.com
TYPE:mouse anti human
CLONE NAME:X107
PROTEIN:Leu2 (CD8)
PROTEIN WEB:https://www.omim.org/entry/186910
ANTIGEN USED:Synthetic peptide ( the 13 c-terminal residues of the cytoplasmic domain of human CD8a)
FUSION PARTNER:P3/NS1/1-Ag4.1
ISOTYPE:Not known
SPECIES REACTIVITY:Human
PREPARATION AND STORAGE:Aliquot and store at 4C. Do not freeze
COMMERCIALIZED BY:Ximbio.com
APP RECOMMENDED:FACS IHC

DESCRIPTION

Leu-2 (CD8) is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells which make up 30% of circulating T cells. X107 may be used to detect these cells in tissue sections and also their neoplastic counterparts.

REFERENCES

Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. p 1076. ISBN-13: 978-0192618672