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mAbs Against HUMAN Protein

LILRB1

CONTACT INFORMATION:University of Oxford marketed by Ximbio.com
TYPE:mouse anti human
CLONE NAME:VMP55
PROTEIN:Leukocyte Immunogolobulin-like Receptor subfamily B member 1 (LILRB1, CD85)
PROTEIN WEB:https://www.omim.org/entry/604811
ANTIGEN USED:Hairy cell leukaemia cells
FUSION PARTNER:P3/NS1/1-Ag4.1
ISOTYPE:IgG1 kappa
SPECIES REACTIVITY:Human
PREPARATION AND STORAGE:Aliquot and store at 4C. Do not freeze
COMMERCIALIZED BY:Ximbio.com
APP RECOMMENDED:FACS IP WB

DESCRIPTION

LILRB1 is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. The functional role of LILRB1 has not been fully elucidated.

PUBLICATION DESCRIBING ANTIBODY CHARACTERIZATION/VALIDATION

Clin Exp Immunol. 1991 Sep;85(3):429-35.
A 72-kD B cell-associated surface glycoprotein expressed at high levels in hairy cell leukaemia and plasma cell neoplasms.
Pulford K1, Micklem K, Thomas J, Jones M, Mason DY.
PMID: 1893623
https://www.ncbi.nlm.nih.gov/pubmed/1893623