EuroMAbNet: European Monoclonal Antibodies NetworkEuroMAbNet. European Monoclonal Antibodies Network

☰ Menu

mAbs Against HUMAN Protein

TAL1

CONTACT INFORMATION:University of Oxford marketed by Ximbio.com
TYPE:mouse anti human
CLONE NAME:BTL73
PROTEIN:T-cell acute lymphocytic leukemia 1
PROTEIN WEB:https://www.omim.org/entry/187040
ANTIGEN USED:TAL-1 recombinant protein
FUSION PARTNER:P3/NS1/1-Ag4.1
ISOTYPE:IgG1
SPECIES REACTIVITY:Human
PREPARATION AND STORAGE:Aliquot and store at 4C. Do not freeze
COMMERCIALIZED BY:Ximbio.com
APP RECOMMENDED:ChIP ELISA IHC WB

DESCRIPTION

T-cell acute lymphocytic leukemia protein 1 (TAL1) is a basic helix-loop-helix transcription factor implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation, including a positive regulation of erythroid differentiation. Diseases associated with TAL1 include leukemia, acute lymphoblastic and precursor t-cell acute lymphoblastic leukemia. A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL).

PUBLICATION DESCRIBING ANTIBODY CHARACTERIZATION/VALIDATION

Blood. 1995 Feb 1;85(3):675-84.
Expression of TAL-1 proteins in human tissues.
Pulford K1, Lecointe N, Leroy-Viard K, Jones M, Mathieu-Mahul D, Mason DY.
PMID: 7833471
https://www.ncbi.nlm.nih.gov/pubmed/7833471