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mAbs Against HUMAN Protein

Integrin aX

CONTACT INFORMATION:University of Oxford marketed by Ximbio.com
TYPE:mouse anti human
CLONE NAME:KB90
PROTEIN:Integrin aX
PROTEIN WEB:https://www.omim.org/entry/151510
ANTIGEN USED:Hairy cell leukaemia cells
FUSION PARTNER:P3/NS1/1-Ag4.1
ISOTYPE:IgG1 kappa
SPECIES REACTIVITY:Human
PREPARATION AND STORAGE:Aliquot and store at 4C. Do not freeze
COMMERCIALIZED BY:Ximbio.com
APP RECOMMENDED:FACS IHC WB

DESCRIPTION

Integrin aX is found on hairy cell leukaemias and malignant histiocytes and on tissue macrophages, monocytes, activated neutrophils and some T-cell clones. Integrin aX has utility for diagnsis of hariy cell leukaemia

PUBLICATION DESCRIBING ANTIBODY CHARACTERIZATION/VALIDATION

Immunology. 1986 Nov;59(3):427-31.
A monoclonal antibody recognizing the p150/95 leucocyte differentiation antigen.
MacDonald SM, Pulford K, Falini B, Micklem K, Mason DY.
PMID: 2431998
https://www.ncbi.nlm.nih.gov/pubmed/2431998

APPLICATIONS

IHC Techniques
IHC Techniques Clone Dilution Antibody concentration Antigen retrieval method Visualization kit +/- control Protein localization Positivity in other species Protocol
Frozen tissue and cytospins
Paraffin tissue
KB90 neat supernatant Citrate Dako Envision Tonsil /
Immunofluorescence
Enlarge image
KB90 Tonsil
Tonsil stained with neat supernatant from KB90 hybridoma, detection using Dako Envision kit, 20x power image