mAbs Against HUMAN Protein
|CONTACT INFORMATION:||Center for Proteomics, University of Rijeka|
|CLONE NAME:|| hVSTM1.07|
|ANTIGEN USED:||hVSTM1 ectodomain |
|FUSION PARTNER:||hIgG1 Fc|
|PREPARATION AND STORAGE:||Long term -20 °C, short term +4 °C. Avoid freeze-thaw cycles.|
|APP RECOMMENDED:||Flow cytometry|
V-set and transmembrane domain containing 1 (VSTM1) encodes two main splicing isoforms, VSTM1-v1 and VSTM1-v2 (Guo, Cell Immunol 2012, 278: 136–142; Steevels, J Immunol. 2010;184:4741–8). VSTM1-v1 is a type I membrane molecule and is mainly expressed in human peripheral blood granulocytes and monocytes (Steevels, J Immunol. 2010;184:4741–8). VSTM1-v2 is a soluble protein that can promote the differentiation and activation of Th17 cells (Guo, Cell Immunol 2012, 278: 136–142). In addition, VSTM1 expression has been associated with rheumatoid arthritis and tumors (Wang, 2016, PLoS ONE 11(1); Zhou, 2016, Apoptosis 21(10):1179-90). Our anti-hVSTM1 antibody hVSTM1.07 works in ELISA (on immunogen) and in FACS (on human cells).
||Type of fluorocrom
|| / isotype control antibody
- Anti human VSTM1 antibody (clone VSTM1.07)
- Overlay histogram showing CD14+ hPBMCs stained with 1:100 VSTM1.07 Ab (red line) and FITC-conjugated anti-mouse IgG. Isotype control antibody (black line) was mouse IgG used under the same conditions.